Basic Information
| LncRNA/CircRNA Name | LINC00161 |
| Synonyms | LINC00161, C21orf100, NCRNA00161 |
| Region | GRCh38_21:28539318-28540355 |
| Ensemble | ENSG00000226935 |
| Refseq | NR_026552 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, in vitro knockdown etc. |
| Sample | hepatocellular carcinoma tissues, cell lines (HepG2, Hep3B, Huh7 and SMMC7721) |
| Expression Pattern | up-regulated |
| Function Description | The result showed that the expression level of LINC00161 was significantly higher in HCC tissues. Further analysis indicated that HCC patients with higher LINC00161 expression have shorter survival. |
| Pubmed ID | 28915581 |
| Year | 2017 |
| Title | Up-regulation of LINC00161 correlates with tumor migration and invasion and poor prognosis of patients with hepatocellular carcinoma |
External Links
| Links for LINC00161 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |