Basic Information
| LncRNA/CircRNA Name | LINC00173 |
| Synonyms | NA |
| Region | GRCh38_12:116533422-116536518 |
| Ensemble | ENSG00000196668 |
| Refseq | NR_027345 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR |
| Sample | TNBC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00173 functions as an oncogene in TNBC through antagonization of miR-490-3p. Upregulation of LINC00173 is associated with poor prognosis in TNBC. |
| Pubmed ID | 32058222 |
| Year | 2020 |
| Title | LncRNA LINC00173 enhances triple-negative breast cancer progression by suppressing miR-490-3p expression |
External Links
| Links for LINC00173 | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |