Basic Information
| LncRNA/CircRNA Name | LINC00174 |
| Synonyms | NA |
| Region | GRCh38_7:66376044-66493566 |
| Ensemble | ENSG00000179406 |
| Refseq | NR_026873 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-qPCR, Western blot |
| Sample | glioma tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | the expression level of LINC00174 was higher in glioma tissues, and LINC00174 down-regulation could remarkably prevent cell proliferation and promote cell apoptosis in both glioma cells and TMZ-resistant glioma cells. |
| Pubmed ID | 31713817 |
| Year | 2019 |
| Title | LINC00174 down-regulation decreases chemoresistance to temozolomide in?human glioma cells by?regulating miR-138-5p/SOX9 axis |
External Links
| Links for LINC00174 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |