Basic Information
| LncRNA/CircRNA Name | LINC00277 |
| Synonyms | EWSAT1, LINC00277, NCRNA00277, TMEM84 |
| Region | GRCh38_15:69072926-69095820 |
| Ensemble | ENSG00000212766 |
| Refseq | NR_026949 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR, RNAi, Cell proliferation assay etc. |
| Sample | cell lines (PC9, PC9G) |
| Expression Pattern | down-regulated |
| Function Description | EWAST1 (LINC00227) is downregulated in PC9G cells and overexpressed EWAST1 also lead to increased sensitivity of PC9G cells to gefitinib. |
| Pubmed ID | 28040594 |
| Year | 2017 |
| Title | Transcriptome analysis of EGFR tyrosine kinase inhibitors resistance associated long noncoding RNA in non-small cell lung cancer. |
External Links
| Links for LINC00277 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |