Basic Information
| LncRNA/CircRNA Name | LINC00277 |
| Synonyms | EWSAT1, LINC00277, NCRNA00277, TMEM84 |
| Region | GRCh38_15:69072926-69095820 |
| Ensemble | ENSG00000212766 |
| Refseq | NR_026949 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | Microarray analysis, qRT-PCR, Western blot, RNAi |
| Sample | cervical cancer tissues, cell lines (HeLa) |
| Expression Pattern | down-regulated |
| Function Description | Both lincRNAs investigated display a significantly reduced pattern of expression in cervical lesions and cancer, associated with clinical parameters. A connection between HPV presence and lincRNAs was noted. hrHPV-positive samples exhibit significantly reduced LINC01101 and LINC00277 expression level. |
| Pubmed ID | 28767188 |
| Year | 2017 |
| Title | LINC01101 and LINC00277 expression levels as novel factors in HPV-induced cervical neoplasia. |
External Links
| Links for LINC00277 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |