Basic Information
| LncRNA/CircRNA Name | LINC00309 |
| Synonyms | NCRNA00309 |
| Region | GRCh38_2:64185078-64205485 |
| Ensemble | ENSG00000230923 |
| Refseq | NR_033837 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, other |
| Sample | BC tissue |
| Expression Pattern | up-regulated |
| Function Description | LINC00309 high expression was an independent predictor for worse disease-free survival and associated with a shorter disease-free survival, especially in hormone-positive breast cancer patients. Also LINC00309 high expression was associated with a shorter disease-free survival both in selective estrogen receptor modulator related hormone therapy (p = 0.025) and aromatase inhibitors related hormone therapy (p = 0.048). Moreover, LINC00309 was an independent predictor of worse disease-free survival in hormone-receptor positive breast cancer patients on univariate and multivariate analyses. |
| Pubmed ID | 31406486 |
| Year | 2019 |
| Title | LINC00309 Is Associated With Short Disease-Free Survival in Breast Cancer |
External Links
| Links for LINC00309 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |