Basic Information
| LncRNA/CircRNA Name | LINC00324 |
| Synonyms | NA |
| Region | GRCh38_17:8220642-8224043 |
| Ensemble | ENSG00000178977 |
| Refseq | NR_026951 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Western blot analysis, qRT-PCR, Dual Luciferase Assay |
| Sample | colorectal cell NCM460 and CRC cell lines SW620, HCT15, SW480 and HCT116 |
| Expression Pattern | up-regulated |
| Function Description | the expression of LIN00324 was increased while miR-214-3p was decreased in CRC cells. Knockdown of LIN00324 suppressed proliferation, migration and invasion in SW620 and HCT15 cells.miR-214-3p as directly target of LINC00324 and the expression of miR-214-3p was downregulated by LINC00324. |
| Pubmed ID | 31858541 |
| Year | 2019 |
| Title | Knockdown of Long Non-Coding RNA LINC00324 Inhibits Proliferation, Migration and Invasion of Colorectal Cancer Cell via Targeting miR-214-3p |
External Links
| Links for LINC00324 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |