Basic Information
| LncRNA/CircRNA Name | LINC00337 |
| Synonyms | NA |
| Region | GRCh38_1:6236240-6239444 |
| Ensemble | ENSG00000225077 |
| Refseq | NR_103534 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | Cisplatin | |
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc. |
| Sample | ESCC tissue ,cell lines (Eca-109, Ec9706, YES-2, and CaES-17) |
| Expression Pattern | up-regulated |
| Function Description | LINC00337 expression is upregulated in ESCC tissues and cells.Upregulation of LINC00337 promotes TPX2 expression by recruiting E2F4 |
| Pubmed ID | 32239565 |
| Year | 2020 |
| Title | Long Non-Coding RNA LINC00337 Induces Autophagy and Chemoresistance to Cisplatin in Esophageal Squamous Cell Carcinoma Cells via Upregulation of TPX2 by Recruiting E2F4 |
External Links
| Links for LINC00337 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |