Basic Information
| LncRNA/CircRNA Name | LINC00339 |
| Synonyms | LINC00339, HSPC157, NCRNA00339 |
| Region | GRCh38_1:22024558-22031223 |
| Ensemble | ENSG00000218510 |
| Refseq | NR_023918 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | cell lines (U87,U251), glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | Knockdown of LINC00339 inhibited glioma cell proliferation, migration, invasion, and tube formation,meanwhile downregulating the expression of VM-related molecular MMP-2 and MMP-14.TWIST1 upregulated the promoter activities of MMP-2 and MMP-14. |
| Pubmed ID | 29499931 |
| Year | 2017 |
| Title | Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis. |
External Links
| Links for LINC00339 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |