Basic Information
| LncRNA/CircRNA Name | LINC00341 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR |
| Sample | gastric cancer tissue, cell lines (MGC-803, BGC-823, SGC-7901) |
| Expression Pattern | down-regulated |
| Function Description | a qRT-PCR assay indicated that the relative expression level of LINC00341 were significantly down-regulated in gastric cancer tissues compared to matched adjacent normal tissues. A Kaplan-Meier analysis showed that low expression of LINC00341 was significantly correlated with shorter overall survival (OS) of gastric cancer patients. Furthermore, an in vitro assay indicated that the over-expression of LINC00341 inhibited cell growth and migration and induced cell apoptosis in gastric cancer. |
| Pubmed ID | 31949815 |
| Year | 2018 |
| Title | Down-regulation of LINC00341 Predicts a Poor Prognosis and Acts as a Tumor Suppressor in Gastric Cancer. |
External Links
| Links for LINC00341 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |