Basic Information
| LncRNA/CircRNA Name | LINC00461 |
| Synonyms | NA |
| Region | GRCh38_5:88507546-88691041 |
| Ensemble | ENSG00000245526 |
| Refseq | NR_024384 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | rectal cancer |
| ICD-0-3 | NA |
| Methods | RT-qPCR, RIP |
| Sample | rectal cancer cell lines (SW1463, HR8348, SW837) |
| Expression Pattern | up-regulated |
| Function Description | LINC00461 expression was upregulated in rectal cancer cells.LINC00461 mediates cisplatin resistance of rectal cancer by targeting miR-593-5p/CCND1 axis, shedding new light on the treatment of rectal cancer. |
| Pubmed ID | 31972361 |
| Year | 2020 |
| Title | Long noncoding RNA LINC00461 mediates cisplatin resistance of rectal cancer via miR-593-5p/CCND1 axis |
External Links
| Links for LINC00461 | GenBank HGNC NONCODE |
| Links for rectal cancer | OMIM COSMIC |