Basic Information
LncRNA/CircRNA Name | LINC00467 |
Synonyms | NA |
Region | GRCh38_1:211382803-211435333 |
Ensemble | ENSG00000153363 |
Refseq | NR_026761 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | glioma |
ICD-0-3 | NA |
Methods | qRT-PCR |
Sample | glioma tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | LINC00467 was upregulated in glioma. The knockdown of LINC00467 attenuated proliferative and invasive abilities, and induced apoptosis in U87 and U251 cells. LINC00467 could bind miRNA-485-5p and negatively regulate its level. Moreover, miRNA-485-5p was responsible for the development of glioma influenced by LINC00467. |
Pubmed ID | 32016980 |
Year | 2020 |
Title | LINC00467 promotes proliferation and invasion in glioma via interacting with miRNA-485-5p |
External Links
Links for LINC00467 | GenBank HGNC NONCODE |
Links for glioma | OMIM COSMIC |