Basic Information
| LncRNA/CircRNA Name | LINC00473 |
| Synonyms | NA |
| Region | GRCh38_6:165908802-165988048 |
| Ensemble | ENSG00000223414 |
| Refseq | NR_026860 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot |
| Sample | HCC tissues,cell lines (SK-HEP-1 and Hep3B) |
| Expression Pattern | up-regulated |
| Function Description | LINC00473 contributed to radioresistance in HCC via modulating the miR-345-5p/FOXP1 axis, which might provide a promising diagnostic marker for HCC radiotherapy. |
| Pubmed ID | 32021265 |
| Year | 2020 |
| Title | Knockdown of LINC00473 Enhances Radiosensitivity in Hepatocellular Carcinoma via Regulating the miR-345-5p/FOXP1 Axis |
External Links
| Links for LINC00473 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |