Basic Information
| LncRNA/CircRNA Name | LINC00525 |
| Synonyms | NA |
| Region | GRCh38_7:47761476-47766772 |
| Ensemble | ENSG00000146666 |
| Refseq | NR_038407 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot |
| Sample | NSCLC tissues,cell lines (A549, NCI-H1299, SPC-A1and HCC827) |
| Expression Pattern | up-regulated |
| Function Description | LINC00525 served as a molecular sponge for miR-338-3p, and modulated expression of endogenous miR-338-3p-targeted insulin receptor substrate 2(IRS2). |
| Pubmed ID | 31991382 |
| Year | 2020 |
| Title | Long non-coding RNA LINC00525 promotes the non-small cell lung cancer progression by targeting miR-338-3p/IRS2 axis |
External Links
| Links for LINC00525 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |