Basic Information
| LncRNA/CircRNA Name | LINC00662 |
| Synonyms | NA |
| Region | GRCh38_19:27684580-27793940 |
| Ensemble | ENSG00000261824 |
| Refseq | NR_027301 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | chordoma |
| ICD-0-3 | C11.9 |
| Methods | qRT-PCR, Western blot |
| Sample | chordoma tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00662 participated in the malignant progression of chordoma by the promotion of RNF144B by acting as a sponge of miR-16-5p, suggesting that LINC00662 was a promising therapeutic target for chordoma. |
| Pubmed ID | 32096180 |
| Year | 2020 |
| Title | LINC00662 triggers malignant progression of chordoma by the activation of RNF144B via targeting miR-16-5p |
External Links
| Links for LINC00662 | GenBank HGNC NONCODE |
| Links for chordoma | OMIM COSMIC |