Basic Information
| LncRNA/CircRNA Name | LINC00668 |
| Synonyms | NA |
| Region | GRCh38_18:6919496-6929966 |
| Ensemble | ENSG00000265933 |
| Refseq | NR_034100 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | qPCR, other |
| Sample | LSCC tisssues and cell lines (TU177, TU212, TU686 and AMC-HN-8) |
| Expression Pattern | up-regulated |
| Function Description | Furthermore, correlation analysis demonstrated that expression levels of LINC00668 were associated with age, pathological differentiation degree, T stage, clinical stage and cervical lymph node metastasis. Moreover, a series of bioinformatics tools and in vitro experiments proved that knockdown of LINC00668 inhibited the proliferation, migration and invasion ability of LSCC cells. |
| Pubmed ID | 30415008 |
| Year | 2019 |
| Title | Expression Profile Analysis Identifies the Long Non-Coding RNA Landscape and the Potential Carcinogenic Functions of LINC00668 in Laryngeal Squamous Cell Carcinoma |
External Links
| Links for LINC00668 | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell cancer | OMIM COSMIC |