Basic Information
| LncRNA/CircRNA Name | LINC00673 |
| Synonyms | NA |
| Region | GRCh38_1:29554-31109 |
| Ensemble | |
| Refseq | NR_036488 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RIP |
| Sample | papillary thyroid carcinoma tissues, human thyroid epithelial cell line (Nthy-o-ri3-1), PTC cell lines (K1, TPC-1 and BCPAP) |
| Expression Pattern | up-regulated |
| Function Description | LINC00673 expression in PTC tissues was significantly higher than that of the adjacent normal tissues. Besides, higher expression of LINC00673 indicated worse prognosis of PTC. |
| Pubmed ID | 30915752 |
| Year | 2019 |
| Title | LncRNA LINC00673 inhibits p53 expression by interacting with EZH2 and DNMT1 in papillary thyroid carcinoma. |
External Links
| Links for LINC00673 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |