Basic Information
| LncRNA/CircRNA Name | LINC00880 |
| Synonyms | AK311218 |
| Region | GRCh38_3:157081667-157123004 |
| Ensemble | ENSG00000243629 |
| Refseq | NR_034007 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | spinal cord ependymoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | spinal cord ependymoma tissues, cell line (SCE) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA LINC00880 targeting CACNG5 inhibits cell apoptosis and promotes proliferation,migration, and invasion in SCE through the MAPK signaling pathway. |
| Pubmed ID | 29215699 |
| Year | 2017 |
| Title | LncRNA LINC00880 promotes cell proliferation, migration, and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma. |
External Links
| Links for LINC00880 | GenBank HGNC NONCODE |
| Links for spinal cord ependymoma | OMIM COSMIC |