Basic Information
| LncRNA/CircRNA Name | LINC00899 |
| Synonyms | NA |
| Region | GRCh38_22:46039907-46044853 |
| Ensemble | ENSG00000231711 |
| Refseq | NR_027036 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, |
| Sample | BC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | LINC00899 overexpression suppresses proliferation, migration and invasion of breast cancer cells in vitro. Moreover, LINC00899 was found to competitively bind miR-425, thereby functioning as a tumor suppressor by enhancing DICER1. |
| Pubmed ID | 31739288 |
| Year | 2019 |
| Title | Long noncoding RNA LINC00899 suppresses breast cancer progression by inhibiting miR-425 |
External Links
| Links for LINC00899 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |