Basic Information
| LncRNA/CircRNA Name | LINC00958 |
| Synonyms | NA |
| Region | GRCh38_11:12961842-12989548 |
| Ensemble | ENSG00000251381 |
| Refseq | NR_038904 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qRT-qPCR, Western blot |
| Sample | LAD tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LINC00958 was found notably overexpressed in LAD, which was associated with the stimulation of its promoter activity induced by SP1. LINC00958 might drive LAD progression via mediating miR-625-5p/CPSF7 axis, indicating the potential of targeting LINC00958 for the treatment of LAD. |
| Pubmed ID | 31997940 |
| Year | 2020 |
| Title | SP1 induced long non-coding RNA LINC00958 overexpression facilitate cell proliferation, migration and?invasion in lung adenocarcinoma via?mediating miR-625-5p/CPSF7 axis |
External Links
| Links for LINC00958 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |