Basic Information
| LncRNA/CircRNA Name | LINC00963 |
| Synonyms | NA |
| Region | GRCh38_9:129483451-129513686 |
| Ensemble | ENSG00000204054 |
| Refseq | NR_038955 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RT-PCR, Western blot, RIP |
| Sample | breast cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We show that LINC00963 upregulation is correlated with aggressive parameters of breast cancer.LINC00963 promotes tumorigenesis and radioresistance in breast cancer through interplay with miR-324-3p and derepression of ACK1. |
| Pubmed ID | 31751910 |
| Year | 2019 |
| Title | LncRNA LINC00963 Promotes Tumorigenesis and Radioresistance in Breast Cancer by Sponging miR-324-3p and Inducing ACK1 Expression |
External Links
| Links for LINC00963 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |