Basic Information
| LncRNA/CircRNA Name | LINC00968 |
| Synonyms | NA |
| Region | GRCh38_8:56496246-56559823 |
| Ensemble | ENSG00000246430 |
| Refseq | NR_038236 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Luciferase reporter assay, RIP, Western blot |
| Sample | breast cancer tissues,cell line (MCF-7, MCF-7/ADM) |
| Expression Pattern | down-regulated |
| Function Description | WNT2 expression exhibited at a high level, whereas LINC00968 at a low expression in breast cancer which was also associated with poor prognosis in patients. |
| Pubmed ID | 30791958 |
| Year | 2019 |
| Title | Long non-coding RNA LINC00968 attenuates drug resistance of breast cancer cells through inhibiting the Wnt2/?-catenin signaling pathway by regulating WNT2. |
External Links
| Links for LINC00968 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |