Basic Information
| LncRNA/CircRNA Name | LINC01088 |
| Synonyms | NA |
| Region | GRCh38_4:78971748-79308798 |
| Ensemble | ENSG00000249307 |
| Refseq | NR_038342 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | epithelial ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, other |
| Sample | EOC tissues |
| Expression Pattern | down-regulated |
| Function Description | Then, the results of RT-PCT confirmed that the expression levels of LINC01088 were significantly lower in EOC tissues compared to adjacent noncancerous tissues . Interestingly, lower LINC01088 expression levels were associated with FIGO stage, grade and distant metastasis . Moreover, Kaplan-Meier analysis indicated that patients with low LINC01088 expression had a poor overall survival. Finally, univariate and multivariate analysis show that LINC01088 expression is an independent predictor for overall survival. |
| Pubmed ID | 30280763 |
| Year | 2018 |
| Title | The Down-Regulation of Long Non-Coding RNA LINC01088 Is Associated With the Poor Prognosis of Epithelial Ovarian Cancer Patients |
External Links
| Links for LINC01088 | GenBank HGNC NONCODE |
| Links for epithelial ovarian cancer | OMIM COSMIC |