Basic Information
LncRNA/CircRNA Name | LINC01101 |
Synonyms | FLJ14816 |
Region | GRCh38_2:120464335-120466218 |
Ensemble | ENSG00000280409 |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | cervical cancer |
ICD-0-3 | C53 |
Methods | Microarray analysis, qRT-PCR, Western blot, RNAi |
Sample | cervical cancer tissues, cell lines (HeLa) |
Expression Pattern | down-regulated |
Function Description | Both lincRNAs investigated display a significantly reduced pattern of expression in cervical lesions and cancer, associated with clinical parameters. A connection between HPV presence and lincRNAs was noted. hrHPV-positive samples exhibit significantly reduced LINC01101 and LINC00277 expression level. |
Pubmed ID | 28767188 |
Year | 2017 |
Title | LINC01101 and LINC00277 expression levels as novel factors in HPV-induced cervical neoplasia. |
External Links
Links for LINC01101 | GenBank HGNC NONCODE |
Links for cervical cancer | OMIM COSMIC |