Basic Information
| LncRNA/CircRNA Name | LINC01133 |
| Synonyms | NA |
| Region | GRCh38_1:159961218-159984750 |
| Ensemble | ENSG00000224259 |
| Refseq | NR_038849 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, RIP |
| Sample | breast cancer tissues,cell lines (MDA-MB-231, SKBR-3, MDA-MB-468, ZR-75-1, BT474, MCF-7,T47D,MCF-10A) |
| Expression Pattern | down-regulated |
| Function Description | In this study, we found that the LINC01133 expression was significantly down-regulated in breast cancer samples and was associated with progression and poor prognosis of breast cancer. |
| Pubmed ID | 31557401 |
| Year | 2019 |
| Title | LINC01133 inhibits breast cancer invasion and metastasis by negatively regulating SOX4 expression through EZH2. |
External Links
| Links for LINC01133 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |