Basic Information
| LncRNA/CircRNA Name | LINC01133 |
| Synonyms | NA |
| Region | GRCh38_1:159961218-159984750 |
| Ensemble | ENSG00000224259 |
| Refseq | NR_038849 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR ect. |
| Sample | ESCC cell lines (KYSE-140, KYSE-150, KYSE-180, KYSE-30, KYSE-410, KYSE-510, KYSE-520, EC-18, and HKESC1) and an immortalized esophageal epithelial cell line (NE-1), ESCC tissues and paired normal tissues |
| Expression Pattern | down-regulated |
| Function Description | LINC01133 expression levels were frequently lower in ESCC tissues and cell lines than in paired normal tissues and an immortalized esophageal epithelial cell line, respectively. LINC01133 was an independent protective factor and had an anti-tumor effect in the early stage of ESCC development.drinking status in our cohort impaired the predictive accuracy of LINC01133 for patients with ESCC |
| Pubmed ID | 30007982 |
| Year | 2018 |
| Title | Predictive Value of LINC01133 for Unfavorable Prognosis was Impacted by Alcohol in Esophageal Squamous Cell Carcinoma. |
External Links
| Links for LINC01133 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |