Basic Information
| LncRNA/CircRNA Name | LINC01234 |
| Synonyms | NA |
| Region | GRCh38_12:113679459-113773683 |
| Ensemble | ENSG00000249550 |
| Refseq | NR_110026 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | multiple myeloma |
| ICD-0-3 | C42.1 |
| Methods | qRT-PCR, Western blot, RIP |
| Sample | MM tissues,cell lines (RPMI-8226, U266, MM.1S and H929) |
| Expression Pattern | up-regulated |
| Function Description | LINC01234 was over-expressed in tumor tissues of MM patients, and LINC01234 down-regulation remarkably inhibited cell proliferation, cycle progression and promoted cell apoptosis in MM cells. |
| Pubmed ID | 31737211 |
| Year | 2019 |
| Title | LINC01234 promotes multiple myeloma progression by regulating miR-124-3p/GRB2 axis |
External Links
| Links for LINC01234 | GenBank HGNC NONCODE |
| Links for multiple myeloma | OMIM COSMIC |