Basic Information
| LncRNA/CircRNA Name | LINC01433 |
| Synonyms | LOC728228 |
| Region | GRCh38_20:4193065-4195943 |
| Ensemble | ENSG00000230176 |
| Refseq | NR_033917 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, RNAi etc. |
| Sample | lung cancer tissues, cell lines (BEAS-2B, A549, H1299, H520 and PC9) |
| Expression Pattern | up-regulated |
| Function Description | Linc01433 was significantly overexpressed in NSCLC tissues compared to normal lung tissues. In addition, linc01433 levels were associated with smoking history. Linc01433 overexpression in lung cancer cells increased proliferation, migration, and invasion abilities, as well as epithelial-to-mesenchymal transition. |
| Pubmed ID | 29532622 |
| Year | 2018 |
| Title | Long non-coding RNA linc01433 promotes migration and invasion in non-small cell lung cancer. |
External Links
| Links for LINC01433 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |