Basic Information
| LncRNA/CircRNA Name | LINC01554 |
| Synonyms | NA |
| Region | GRCh38_5:95852232-95860133 |
| Ensemble | ENSG00000236882 |
| Refseq | NR_026936 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | HCC tissue,cell line |
| Expression Pattern | down-regulated |
| Function Description | LINC01554 was frequently downregulated in HCC, which was significantly associated with tumor invasion (P = 0.005), tumor size (P = 0.041), tumor staging (P = 0.023) and shorter survival (P = 0.035) of HCC patients. |
| Pubmed ID | 30809309 |
| Year | 2019 |
| Title | LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway. |
External Links
| Links for LINC01554 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |