Basic Information
| LncRNA/CircRNA Name | LINC01561 |
| Synonyms | C10orf85 |
| Region | GRCh38_10:120597949-120600124 |
| Ensemble | ENSG00000177234 |
| Refseq | NR_103717 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot, luciferase reporter assay, etc. |
| Sample | The human embryonic kidney cell line (293 T), BrCa cell lines (MCF7, BT-20, ZR-75-1, MX-1), human breast epithelial cell line (MCF-10). |
| Expression Pattern | down-regulated |
| Function Description | In summary, the findings of this study, based on ceRNA theory, combining the research foundation of miR-145-5p and MMP11, and taking linc01561 as a new study point, provide new insight into molecular-level reversing proliferation and apoptosis of BrCa. |
| Pubmed ID | 29890225 |
| Year | 2018 |
| Title | Mixomics analysis of breast cancer: Long non-coding RNA linc01561 acts as ceRNA involved in the progression of breast cancer. |
External Links
| Links for LINC01561 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |