Basic Information
| LncRNA/CircRNA Name | LINC01980 |
| Synonyms | NA |
| Region | GRCh38_3:27797563-27931579 |
| Ensemble | ENSG00000225548 |
| Refseq | NR_146630 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc. |
| Sample | ESCC tissues and adjacent normal tissues, cell lines (TE1, ECA109, KYSE30,KYSE170, KYSE150, and YES2) |
| Expression Pattern | up-regulated |
| Function Description | The high expression of LINC01980 was detected in ESCC tissues and cells, and predicted poor prognosis. LINC01980 promoted the cell proliferation, migration, invasion ability and epithelial-mesenchymal transition (EMT) progress in ESCC cells. In addition, a negative correlation between LINC01980 and miR-190a5p or miR-190a-5p and MYO5A was observed in ESCC |
| Pubmed ID | 32325088 |
| Year | 2020 |
| Title | LINC01980 facilitates esophageal squamous cell carcinoma progression via regulation of miR-190a-5p/MYO5A pathway. |
External Links
| Links for LINC01980 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |