Basic Information
| LncRNA/CircRNA Name | LINC02042 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Western blot |
| Sample | ESCC tissues,cell lines,blood |
| Expression Pattern | up-regulated |
| Function Description | linc02042 acted as a scaffold for YBX-1 binding to the 3??UTR of c-Myc mRNA, leading to enhanced c-Myc mRNA stability, thereby facilitating ESCC growth and metastasis. |
| Pubmed ID | 32161513 |
| Year | 2020 |
| Title | A novel positive feedback loop of linc02042 and?c-Myc mediated by YBX1 promotes tumorigenesis and metastasis in?esophageal squamous cell carcinoma |
External Links
| Links for LINC02042 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |