Basic Information
| LncRNA/CircRNA Name | AP000221.1 |
| Synonyms | LOC105372753 |
| Region | GRCh38_21:25515473-25518338 |
| Ensemble | ENSG00000229962 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (SW1990, SWl990/GZ etc.) |
| Expression Pattern | up-regulated |
| Function Description | Six lncRNAs (RP11-58D2.1, lincRNA-ZNF532, AP000221.1, CTC-338M12.5, CR619813, DDX6P) were selected to validate the microarray consistency by using qPCR. The results demonstrated that RP11-58D2.1, lincRNA-ZNF532 and AP000221.1 were upregulated and that CTC-338M12.5, DDX6P and CR619813 were downregulated in the SW1990/GZ cells compared with SW1990 cells. |
| Pubmed ID | 25755691 |
| Year | 2015 |
| Title | Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling. |
External Links
| Links for AP000221.1 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |