Basic Information
| LncRNA/CircRNA Name | ABHD11-AS1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000225969 |
| Refseq | NR_026690 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | three characteristic plasma candidate lncRNAs, ABHD11-AS1, LINC00176 and SNHG11, were identified, and their levels were significantly higher in PC patients than in normal controls. We found that among the three candidate lncRNAs, ABHD11-AS1 showed the best diagnostic performance for the detection of PC. Furthermore, ABHD11-AS1 had a higher area under the ROC curve (AUC) than CEA, CA199 and CA125 for early PC diagnosis, while the combination of ABHD11-AS1 and CA199 was more effective than ABHD11-AS1 alone |
| Pubmed ID | 31333792 |
| Year | 2019 |
| Title | Circulating lncRNA ABHD11-AS1 serves as a biomarker for early pancreatic cancer diagnosis |
External Links
| Links for ABHD11-AS1 | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |