Basic Information
| LncRNA/CircRNA Name | LINC-PINT3 |
| Synonyms | LINC-PINT, LincRNA-Pint, MKLN1-AS1, PINT |
| Region | GRCh38_7:130938963-131110176 |
| Ensemble | ENSG00000231721 |
| Refseq | NR_015431 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (A549, H1299 and 293T) |
| Expression Pattern | up-regulated |
| Function Description | The results showed that LINC-PINT3 was significantly up-regulated in the TGF-B treated cells compared with untreated cells, while LINC01186, RP11-8L2.1, TARID and TM4SF1-AS1 were significantly down-regulated. |
| Pubmed ID | 28119085 |
| Year | 2017 |
| Title | Long noncoding RNA LINC01186, regulated by TGF-B/SMAD3, inhibits migration and invasion through Epithelial-Mesenchymal-Transition in lung cancer. |
External Links
| Links for LINC-PINT3 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |