Basic Information
| LncRNA/CircRNA Name | LINC-POU3F3 |
| Synonyms | POU3F3, BRN1, OTF8, brain-1, oct-8 |
| Region | GRCh38_2:104855511-104858574 |
| Ensemble | ENSG00000198914 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | ESCC tissues |
| Expression Pattern | up-regulated |
| Function Description | Further validation in a larger cohort including 205 ESCC patients, 82 patients suffering from esophagus dysplasia and 210 healthy controls confirmed that increased Linc00152, CFLAR-AS1 and POU3F3 might be potential biomarkers for predicting the early progress. We also revealed that circulating levels of three lncRNAs were associated with poor post-surgery prognosis of ESCC patients. |
| Pubmed ID | 27855375 |
| Year | 2016 |
| Title | Three Circulating LncRNA Predict Early Progress of Esophageal Squamous Cell Carcinoma. |
External Links
| Links for LINC-POU3F3 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |