Basic Information
| LncRNA/CircRNA Name | LINC-POU3F3 |
| Synonyms | POU3F3, BRN1, OTF8, brain-1, oct-8 |
| Region | GRCh38_2:104855511-104858574 |
| Ensemble | ENSG00000198914 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | glioma tissues, cell lines (T98G, A172) |
| Expression Pattern | up-regulated |
| Function Description | The results revealed that linc-POU3F3 levels were extraordinarily associated with the tumor WHO grade. In related biochemical assays, overexpression of linc-POU3F3 promotes cell viability and proliferation in glioma cells, whereas knockdown of linc-POU3F3 showed the opposite effetc. |
| Pubmed ID | 25445282 |
| Year | 2014 |
| Title | Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma. |
External Links
| Links for LINC-POU3F3 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |