Basic Information
| LncRNA/CircRNA Name | LINC-POU3F3 |
| Synonyms | POU3F3, BRN1, OTF8, brain-1, oct-8 |
| Region | GRCh38_2:104855511-104858574 |
| Ensemble | ENSG00000198914 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, RNAi, Western blot, Cell proliferation assay etc. |
| Sample | glioma tissues, cell lines (A172, U87-MG, U251, T98G) |
| Expression Pattern | up-regulated |
| Function Description | The levels of linc-POU3F3 were upregulated in glioma tissue and significantly correlated with the advanced tumor stage. A172 cells exhibited the highest expression level. |
| Pubmed ID | 28338200 |
| Year | 2017 |
| Title | Glioma cells promote angiogenesis through the release of exosomes containing long non-coding RNA POU3F3. |
External Links
| Links for LINC-POU3F3 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |