Basic Information
| LncRNA/CircRNA Name | LINCRNA-BC8 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-seq, qPCR etc. |
| Sample | breast cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | We analyzed lincRNAs whose expression was significantly different between cancer tissues and adjacent tissues. LincRNA-BC2 and lincRNA-BC5 were consistently up-regulated more than 2-fold (mean??D) in cancer samples. Whereas, lincRNA-BC4 and lincRNA-BC8 were down-regulated.They might play important roles in the function of oncogenes or tumor suppressors affecting the development and progression of breast cancer. |
| Pubmed ID | 25084155 |
| Year | 2014 |
| Title | Long intergenic non-coding RNAs (LincRNAs) identified by RNA-seq in breast cancer. |
External Links
| Links for LINCRNA-BC8 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |