Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oral cancer |
| ICD-0-3 | C06.9 |
| Methods | qPCR |
| Sample | oral cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | In oral squamous cell carcinomas, for the first time, we observed linc-RoR overexpression, downregulation of miR-145-5p, and overexpression of c-Myc, Klf4, Oct4, and Sox2, suggesting the existence of linc-RoR-mediated competing endogenous RNA network in undifferentiated tumors. |
| Pubmed ID | 28443494 |
| Year | 2017 |
| Title | Expression profiling of long non-coding RNA identifies linc-RoR as a prognostic biomarker in oral cancer |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for oral cancer | OMIM COSMIC |