Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | Liver Cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Our findings indicate that linc-ROR plays an oncogenic role in NSCLC development and may function as a prognostic and predictive biomarker for NSCLC. Cox regression analyses were performed to explore the effect of lincROR as an independent predictor of survival. Fu et al21 reported that linc-ROR promotes pancreatic cancer cell proliferation and invasiveness by sponging some different miRNAs. |
| Pubmed ID | 29028092 |
| Year | 2017 |
| Title | Long non-coding RNA ROR is a novel prognosis factor associated with non-small-cell lung cancer progression. |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |