Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, RIP etc. |
| Sample | cell lines (PANC-1, SW1990) |
| Expression Pattern | up-regulated |
| Function Description | linc-ROR was up-regulated in PDAC tissues and related to poor prognosis.Mechanistically, we found that linc-ROR functioned as a competing endogenous RNA (ceRNA) to several tumor suppressor microRNAs, particularly some members of let-7 family. |
| Pubmed ID | 28580169 |
| Year | 2017 |
| Title | Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for pancreatic cancer | OMIM COSMIC |