Basic Information
| LncRNA/CircRNA Name | LINC-ROR |
| Synonyms | LINC-ROR, ROR, lincRNA-RoR |
| Region | GRCh38_18:57054558-57072119 |
| Ensemble | ENSG00000258609 |
| Refseq | NR_048536 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | lung cancer tissues, cell line (A549) |
| Expression Pattern | up-regulated |
| Function Description | Here, qRT-PCR analysis revealed that p53 and ROR were upregulated while miR-145 was downregulated in non-small cell lung cancer (NSCLC) tissues and LCSCs compared to their paired adjacent normal tissues and lung cancer cells (LCCs). Besides, high p53 level, low miR-145 level, and high ROR level were associated with poor prognosis in NSCLC. |
| Pubmed ID | 28516515 |
| Year | 2017 |
| Title | Interaction of lincRNA ROR and p53/miR-145 correlates with lung cancer stem cell signatures |
External Links
| Links for LINC-ROR | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |