Basic Information
| LncRNA/CircRNA Name | ARAP1-AS1 |
| Synonyms | NA |
| Region | GRCh38_11:72685075-72693808 |
| Ensemble | ENSG00000256007 |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qRT-PCR, Western blot |
| Sample | BC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | ARAP1-AS1 knockdown led to repressed proliferation,strengthened apoptosis and blocked migration of BC cells. ARAP1-AS1 could boost HDAC2 expression in BC through sponging miR-2110 via a ceRNA mechanism. |
| Pubmed ID | 32110804 |
| Year | 2020 |
| Title | Long non-coding RNA ARAP1-AS1 accelerates cell proliferation and migration in breast cancer through miR-2110/HDAC2/PLIN1 axis |
External Links
| Links for ARAP1-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |