Basic Information
| LncRNA/CircRNA Name | lin-RECK-3 |
| Synonyms | SPAAR, LINC00961, SPAR??lin-RECK-3 |
| Region | GRCh38_9:35909483-35937153 |
| Ensemble | ENSG00000235387 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | RNA-seq, qPCR, Western blot etc. |
| Sample | cell lines (A2780, A2780-DR) |
| Expression Pattern | up-regulated |
| Function Description | Here, we showed that expression of lin-RECK-3, H19, LUCAT1, LINC00961, and linc-CARS2-2 was enhanced in cisplatin-resistant A2780-DR cells, Lin-RECK-3, H19, LUCAT1, LINC00961, and linc-CARS2-2 showed significantly increased expression levels in A2780-DR cells. |
| Pubmed ID | 27193186 |
| Year | 2016 |
| Title | The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer. |
External Links
| Links for lin-RECK-3 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |