Basic Information
| LncRNA/CircRNA Name | lnc003875 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | placental site trophoblastic tumor |
| ICD-0-3 | NA |
| Methods | qRT-PCR, Luciferase assay |
| Sample | PSTT tissues,umbilical vein endothelial cells (HUVECs) and HEK-293T cells |
| Expression Pattern | up-regulated |
| Function Description | lnc003875 was highly expressed in PSTT tissues and mainly localized in the cytoplasm of PSTT derived CAFs.lnc003875 exerted a negligible effect on miR-363 expression, but it recovered miR-363-reduced EGR1 expression. |
| Pubmed ID | 31857113 |
| Year | 2020 |
| Title | lnc003875/miR-363/EGR1 Regulatory Network in the Carcinoma -Associated Fibroblasts Controls the Angiogenesis of Human Placental Site Trophoblastic Tumor (PSTT) |
External Links
| Links for lnc003875 | GenBank HGNC NONCODE |
| Links for placental site trophoblastic tumor | OMIM COSMIC |