Basic Information
| LncRNA/CircRNA Name | lncAGER |
| Synonyms | AGER-1 |
| Region | GRCh38_6:32180968-32184324 |
| Ensemble | ENSG00000204305 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qRT-PCR |
| Sample | CRC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | We found that the expression of lnc-AGER-1 in the tumor tissues was significantly down-regulated.lnc-AGER-1 has a suppressive role in colorectal cancer development via modulating AGER, which may serve as a target for colorectal cancer diagnosis and treatment. |
| Pubmed ID | 32031046 |
| Year | 2020 |
| Title | Long non-coding RNA AGER-1 inhibits colorectal cancer progression through sponging miR-182 |
External Links
| Links for lncAGER | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |