Basic Information
| LncRNA/CircRNA Name | lnc-CC3 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Northern blot, ISH etc. |
| Sample | cell lines (SiHa, HeLa, CaSki etc.) |
| Expression Pattern | up-regulated |
| Function Description | Overexpression of lnc-CC3 promoted migration and invasion by SiHa cervical cancer cells in vitro and in vivo, increased Slug expression, and reduced the expression of the epithelial cell marker E-cadherin. Conversely, lnc-CC3 knockdown altered SiHa cell morphology and increased the expression of E-cadherin, thereby suppressing migration and invasion. |
| Pubmed ID | 27223436 |
| Year | 2016 |
| Title | Lnc-CC3 increases metastasis in cervical cancer by increasing Slug expression. |
External Links
| Links for lnc-CC3 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |