Basic Information
| LncRNA/CircRNA Name | lncHERG |
| Synonyms | LOC644794 |
| Region | GRCh38_7:66904120-66906297 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioblastoma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay etc. |
| Sample | GBM cell lines (U87, U251, LN229) |
| Expression Pattern | up-regulated |
| Function Description | LncHERG knockdown impaired cell proliferation, migration and invasion while inhibition of miR-940 in the meantime reversed this trend.In conclusion,our study highlights the essential role of lncHERG in glioblastoma by acting as a competing endogenous RNA of miR-940, which may serve as a new prognostic biomarker in glioblastoma. |
| Pubmed ID | 29296221 |
| Year | 2017 |
| Title | Long noncoding RNA lncHERG promotes cell proliferation, migration and invasion in glioblastoma |
External Links
| Links for lncHERG | GenBank HGNC NONCODE |
| Links for glioblastoma | OMIM COSMIC |