Basic Information
| LncRNA/CircRNA Name | lncRNA00673 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot etc. |
| Sample | HCC tissues, cell lines (HepG2, Hep3B, MHCC-97H) |
| Expression Pattern | up-regulated |
| Function Description | lncRNA00673 expression was significantly up-regulated in 72.7% (40 of 55,fold ??.0) HCC tissues.lncRNA00673 is highly expressed in HCC tissues and cells, and can promote the proliferation and metastasis of HCC by the regulation on Notch signaling pathway. lncRNA00673 may be a potential target for the treatment of HCC. |
| Pubmed ID | 28829500 |
| Year | 2017 |
| Title | Promotion of proliferation and metastasis of hepatocellular carcinoma by LncRNA00673 based on the targeted-regulation of notch signaling pathway. |
External Links
| Links for lncRNA00673 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |